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Microfluidic devices for Point-of-Care (POC) testing: HIV-1 treatment monitoring
 
Time: 2:00 pm
Date: Jun. 12 , 2012
Location:The Institute for Advanced Materials and Nano Biomedicine (iNANO), 67 Chifeng Road
Reporter: Dr. Shuqi Wang ( Harvard Medical School, Harvard University)
Abstract:
It is estimated that there are 33 million people living with HIV-1 worldwide, with the majority of infected individuals in developing countries. To curb the epidemic, the World Health Organization (WHO) is rapidly expanding access to antiretroviral therapy (ART) in resource-limited settings. However, the expansion is significantly restricted by the lack of point-of-care (POC) ART monitoring tools to access the response to antiretroviral drugs and to ensure drug adherence. Standard assays used in developed countries such as CD4 cell count by flow cytometry and HIV-1 viral load by RT-PCR is prohibitively expensive and technologically complex, which limits their wide applications in developing countries, especially at the decentralized clinical settings. In my talk, I will cover the application of microfluidic technology to both CD4 cell count and viral load testing, with an ultimate goal of antiretroviral treatment monitoring at the POC.
 
 

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