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James A. Donovan Ph. D.
 


Xuejun Wen, M.D., Ph.D.

Tepin Professor of The Institute for Advanced Materials and Nano Biomedicine, Tongji University, China.
Tel: 86-21-6598-8029, Fax: 86-21-6598-8029

Hansjörg Wyss Endowed Chair in Regenerative Medicine
Professor of Bioengineering, Clemson University, USA
Professor of Orthopaedic Surgery, Medical University of South Carolina, USA
Professor of Cell Biology and Anatomy, Surgery, Medical University of South Carolina, USA
Professor of Dental Medicine, Medical University of South Carolina, USA
Professor of Hollings Cancer Center, Surgery, Medical University of South Carolina, USA
xjwen@clemson.edu; xuejun@musc.edu
Tel: 1-843-792-5875; Fax: 1-843-792-0664

http://www.sccoee.org/chairs.asp
http://www.clemson.edu/ces/bioe/faculty-staff/directory/wen.html http://regmed.musc.edu/Faculty/WenX.htm http://www.musc.edu/bioengineering/regenerative.html

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EDUCATION

Ph.D. (2003) Bioengineering (Biomedical Polymer & Tissue Engineering)
University of Utah, Salt Lake City, UT, USA

M.S. (2000)Materials Science and Engineering. (Bioceramics)
University of Cincinnati, Cincinnati, OH, USA

M.S. (1997) Materials Science and Engineering. (Metallic Biomaterials)
Zhejiang University, Hangzhou, China

M.D. (1994) Medicine
Henan Medical University, Zhengzhou, China


POSITIONS HELD

2010-Present Hansjörg Wyss Endowed Chair Professor in Regenerative Medicine
2010-Present Professor of Bioengineering, Regenerative Medicine and Cell Biology, Orthopedic Surgery, Dental Medicine, Hollings Cancer Center, Clemson University and Medical University of South Carolina
2008-2010 Associate Professor (With Tenure) in Department of Bioengineering, Clemson University
2008-2010 Associate Professor in Department of Cell Biology & Anatomy; Orthopaedic Surgery, Dental Medicine, Hollings Cancer Center, Medical University of South Carolina
2003-2008  Assistant Professor (Tenure Track) in Department of Bioengineering, Clemson University
2003-2008 Adjunct Assistant Professor in Department of Cell Biology & Anatomy; Medical University of South Carolina
2005-2008  Adjunct Assistant Professor of Orthopedic Surgery at Medical University of South Carolina
1999-2003  Research Assistant at Keck Center for Tissue Engineering (Biomedical Polymer & Tissue Engineering), University of Utah
1997-1999 Research Assistant  of  Material Science & Engineering (Bioceramics) at University of Cincinnati
1994-1997 Research Assistant of Material Science & Engineering (Metallic Biomaterials) at Zhejiang University, China
1993-1994 Resident Doctor at Henan Medical University Hospital, China


PROFESSIONAL RECOGNITION

INVITED GRANT REVIEWERS: NIH/USA, NSF/USA, NASA/USA, Veterans Affairs (VA, USA), American Chemical Society (ACS) Research Fund/USA, American Heart Association (AHA), U.S. Civilian Research & Development Foundation (CRDF), Alzheimer’s Disease Association, North Carolina Biotechnology Center (Science & Technology Development Program), Technology Foundation STW (Netherlands), New York Empire State Stem Cell Program (NYSTEM)
EDITOR-IN-CHIEF (BOOKS): Stem Cell Engineering Handbook
EDITORIAL ADVISORY BOARD: Biofabrication, The Open Biomedical Engineering Journal
GUEST EDITOR (JOURNALS): Materials Science and Engineering - C
INVITED MANUSCRIPT REVIEWERS: Nature, Bone, Journal of Biomedical Materials Research, ASAIO Journal, Artificial Organ, Langmuir, Journals of Materials Science, Biomaterials, Macromolecules, Biomacromolecules, Journal of Nanomaterials, Journal of Nanoscience and Nanotechnology, Nanomedicine, Journals of Materials Science: Materials in Medicine, Acta Biomaterialia, Journal of Neuroscience Methods, Journal of Biomaterial Applications, Open Biomedical Engineering Journal, International Journal of Optomechatronics, Composites Science and Technology, Macromolecular Bioscience, Materials Science and Engineering, Medical Engineering & Physics, Journal of the Royal Society Interface.


HONORS AND AWARDS: 
NSF CAREER AWARD (2008-2013)
McQueen-Quattlebaum Faculty Achievement Award (Clemson University) (2010)
Clemson University Board of Trustees Award for Faculty Excellence (2009)
Clemson University Board of Trustees Award for Faculty Excellence (2008)
Sigma XI Outstanding Young Investigator of the Year (2008)
Wallace H. Coulter Early Career Translational Research Award in Bioengineering (2005)
Stem Cell Research Award from Michael J. Fox Foundation for Parkinson’s Research (2005)
Outstanding Student Research and Travel Award, Society for Biomaterials (2001)
Whitaker Foundation Graduate Fellowship (2001-2002)
Whitaker Foundation Graduate Fellowship (2000-2001)
Graduate Student Recruiting Award, University of Utah (1999-2000)
University Graduate Scholarship, University of Cincinnati (1997-1999)
Chu Kochen Scholarship and Chu Kochen Medal, Zhejiang University (1996)
Excellent Graduate Student Award, Zhejiang Province, China (1997)

Biographical Sketch

Dr. Xuejun Wen is currently a tenured full professor in the department of Bioengineering, Clemson University. He is also the State of South Carolina Named Hansjörg Wyss Endowed Chair Professor in Regenerative Medicine. He joined Clemson Bioengineering as a tenure-track faculty in 2003, and resides in Charleston, SC to initiate joint bioengineering program between the Clemson University and Medical University of South Carolina (CU-MUSC) with the mission to foster translational research, and promote interinstitutional, multidisciplinary collaborations. He is also being appointed as adjunct faculty in a couple of clinical and basic science departments at MUSC, fields including neuroscience, orthopaedic surgery, dental medicine, and cell biology and anatomy. Through the past 8 years of his independent academic career, he has established a strong independent extramurally funded research lab in the field of biomaterials, tissue engineering, stem cells, and regenerative medicine. His research focuses on regenerating functional and safe human tissues by combining the principles of biomaterial science, biological science, stem cell biology, tissue engineering, regenerative medicine with the advanced techniques in molecular and cell biology. Please visit his lab website (http://www.clemson.edu/ces/bioe/faculty-staff/directory/wen.html) for the details of research projects. His lab has been extensively funded by federal organizations, as well as private foundations. Currently, his lab is funded by NIH (R01 awards, and R21 awards), NSF (NSF CAREER award, and NSF research grant), DoD (Office of Naval Research, CDMRP), National Textile Center, Michael J. FOX Foundation for Parkinson’s disease, Wallace H. Coulter Foundation, March of Dimes Foundation, AO Foundation, Orthopedic Trauma Foundation, South Carolina Spinal Cord Injury Research Fund, etc. He has filed over 30 disclosures (with 12 full patent applications). His research has been featured in numerous press releases and was highlighted in the front page of Clemson University, and the front page of the College of Engineering and Science of Clemson University.

SELECTED PUBLICATIONS

pdf Yongzhi Qiu, Ning Zhang, Qian Kang, Yuehuei An, Xuejun Wen; Chemically Modified Light-curable Chitosans with Enhanced Potential for Bone Tissue Repair. Journal of Biomedical Materials Research: Part A (In press; 10.1002/jbm.a.32017)

pdfVince Beachley, Xuejun Wen, Effect of electrospinning parameters on the nanofiber diameter and length, Materials Science and Engineering: C, (In Press, doi:10.1016/j.msec.2008.10.037)

pdfGoutam Koley, Jie Liu, Md. W. Nomani, Moonbin Yim, Xuejun Wen, Tain-Yen Hsia, Miniaturized implantable pressure and oxygen sensors based on polydimethylsiloxane thin films, Materials Science and Engineering: C, (In Press, DOI: 10.1016/j.msec.2008.12.016)

pdfBogdan Zdyrko, Viktor Klep, Xiaowei Li, Qian Kang, Sergiy Minko, Xuejun Wen, Igor Luzinov, Polymer brushes as active nanolayers for tunable bacteria adhesion, Materials Science and Engineering: C, (In Press, DOI: 10.1016/j.msec.2008.12.017)

pdfJing Zhao, Ning Zhang, Glenn D. Prestwich, Xuejun Wen; Recruitment of Endogenous Stem Cells for Tissue Repair; Macromolecule Bioscience; 8; 836 - 842; 2008

pdfTadeusz Wellisz, Yueheui An, Xuejun Wen, Qian Kang, Chris Hill, Jonathan K. Armstrong. Infection rates and healing using bone wax and a soluble polymer material. Clin Orthop Relat Res. 2008 Feb;466(2):481-6. 2008

pdfTadeusz Wellisz, Jonathan K. Armstrong, John Cambridge, Yuehuei H. An, Xuejun Wen, Christopher M. Hill, and Timothy C. Fisher; The Effects of a Soluble Polymer and Bone Wax on Sternal Healing in an Animal Model; Ann Thorac Surg;85:1776–80; 2008

pdfLauren Shora, Selcuk Guceri, Xuejun Wen, Milind Gandhi, Wei Sun; Fabrication of three-dimensional polycaprolactone/ hydroxyapatite tissue scaffolds and osteoblast-scaffold interactions in vitro; Biomaterials; 28(35):5291-7, 2007

pdfYongzhi Qiu, Ning Zhang, Yuehuei H. An, Xuejun Wen; Biomaterial Strategies to Reduce Implant-Associated Infections. International Journal of Artificial Organ; 30(9):828-41, 2007

pdfChangan Guo, Xueguang Liu, Jianzhong Huo, Chun Jiang, Xuejun Wen, and Zhengrong Chen; Novel gene-modified-tissue engineering of cartilage using stable transforming growth factor-beta1-transfected mesenchymal stem cells grown on chitosan scaffolds. J Biosci Bioeng. 103(6):547-56; 2007

pdfChanghong Zhang, Ning Zhang, Xuejun Wen; Synthesis and characterization of biocompatible, degradable, light-curable, polyurethane-based elastic hydrogels.; Journal of Biomedical Materials Research: Part A. 82(3):637-50; 2007

pdfNorris RA, Damon B, Mironov V, Kasyanov V, Ramamurthi A, Moreno-Rodriguez1 R, Trusk T, Potts JD, Goodwin RL, Davis J, Hoffman S, Wen Xuejun, Sugi Y, Kern CB, Mjaatvedt CH, Turner DK, Oka T, Conway SJ, Molkentin JD, Forgacs G, Markwald RR; Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues; Journal of Cellular Biochemistry; 101(3):695-711; 2007

pdfHeather L Nichols, Ning Zhang, Jing Zhang, S. Bhaduri, Donglu Shi, Xuejun Wen; Coating nano-thickness degradable films on nanocrystalline hydroxyapatite particles to improve the bonding strength between nanoHA and degradable polymer matrix. Journal of Biomedical Materials Research: Part A. 82(2):373-82; 2007

pdfGurjarpadhye A, Hewett KW, Justus C, Wen Xuejun, Stadt H, Kirby ML, Sedmera D, Gourdie RG, Neural crest cells are necessary for insulation of the cardiac conduction system, AJP - Heart and Circulatory Physiology; 292(3):H1291-300; 2007

pdfTao Xu, Ning Zhang, Heather L Nichols, Donglu Shi , Xuejun Wen ; Modification of Nanostructured Materials for Biomedical Applications.; Materials Science & Engineering C; 27, 579-594, 2007

pdfNing Zhang, Heather L Nichols, Shila Tylor, Xuejun Wen; Fabrication of nanocrystalline hydroxyapatite doped degradable composite hollow fiber for guided and biomimetic bone tissue engineering; Materials Science & Engineering C; 27(3), 599-606, 2007

pdfChanghong Zhang, Ning Zhang, Xuejun Wen, Improving the elasticity and cytophilicity of biodegradable polyurethane by changing chain extender. Journal of Biomedical Materials Research: Part B. 79(2):335-44; 2006

pdfHeather L Nichols, Ning Zhang, Xuejun Wen. Proteomics and genomics of microgravity. Physiological Genomics. 26(3):163-171, 2006

pdfV. Mironov, V. Kasyanov, M Yost, R Visconti, W Twal, T Trusk, Xuejun Wen, I Ozolanta, A Kadishs, Glenn D Prestwich, L Terracio, Roger Markwald. Cardiovascular Tissue Engineering I. Perfusion Bioreactors: A review. Journal of Long-term Effects of Medical Implants, 16(2):111-130, 2006

pdfV Mironov, Chris Drake, Xuejun Wen; Charleston Bioengineered Kidney Project, Biotechnol. Journal; 1, 903–905, 2006

pdfXuejun Wen and Patrick A Tresco. Fabrication and Characterization of Permeable Degradable Poly(DL-Lactide-co-glycolide) (PLGA) Hollow Fiber Phase Inversion Membranes for Use as Nerve Tract Guidance Channels, Biomaterials; 27(20):3800-9; 2006

pdfXuejun Wen, Patrick A. Tresco; Effect of filament diameter and extracellular matrix molecule precoating on neurite outgrowth and schwann cell behavior on multifilament entubulation bridging device in vitro; Journal of Biomedical Materials Research: Part A. 76(3):626-37, 2006

pdfNing Zhang, Changhong Zhang, and Xuejun Wen; Fabrication of semi-permeable hollow fiber membranes with highly aligned texture for nerve guidance; Journal of Biomedical Materials Research: Part A. 75(4):941-949, 2005

pdfNing Zhang, Honghai Yan, and Xuejun Wen; Tissue engineering strategies for axonal guidance; Brain Research Review; 49(1), 48-64, 2005

pdfB Massey, Xuejun Wen, R Rohr, Patrick A Tresco, L Dahlstrom, AH Park. Resorption rate and biocompatibility characteristics of two polyester ventilation tubes in a guinea pig model. Otolaryngol-Head Neck Surg J 131(6), 921-925, 2004

 

The Institute for Advanced Materials and Nano Biomedicine (iNANO),
Tongji University, 67 Chifeng Road, Shanghai, 200092, China
Tel: +86-021-65988029    Email: inano@tongji.edu.cn
Copyright 2009 Tongji University. All rights reserved.

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