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Yongyong Li, Ph.D. Chao Lin, Ph.D.
Peng Zhao, Ph.D. Jinhu Yang, Ph.D.
Fangfang Guo, Ph.D.
Yilong Wang, Ph.D.
 

 

Yong-Yong Li, Ph.D.

Research Scientist & Director Assistant
The Institute for Advanced Materials & Nano Biomedicine
Tongji University
Address:67 Chifeng Rd. Shanghai, 200092, P.R. China
Tel/Fax:+086-021-65983706-815
Email: yongyong_li(at)tongji(dot)edu(dot)cn

 
 

EDUCATION
2004-2009  MS & Ph. D, Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University, China.
2000-2004  B. S., College of Materials Science and Chemical Engineering, China University of Geosciences, Wuhan, China.

RESEARCH INTEREST
☻ We develop the intelligent nanoparticles whose properties can be responsive to biological signals as well as the manually controlled external stimulus and further seek their biomedical application, especially in drug delivery, such as intracellular drug delivery and treatment for tumor drug resistance.

☻ Inspired by biological counterparts, our interests were centered on the fabrication of new self-assembled polymeric systems with the unique structure and bio-oriented function. For example, we especially interest in the construction of new nanostructures based on host-guest interaction and hydrogen bond interaction.

BIOGRAPHICAL SKETCH
Dr. Yong-Yong Li obtained his PhD at Wuhan University and then joined INANO as an assistant professor in 2009 and now as co-director of research center of cancer. Dr. Li has so far published more than 20 refereed journal publications including Angewandte Chemie-international Edition (IF=11.83), Advanced Materials (IF=8.38), ACS Nano (IF=7.49), Biomaterials (IF=7.37) and Small (IF=6.17). Dr. Li’s work has received much attention from the academic world, for example, his work on Small was preferentially introduced by the journal in the previous issue before publication and the work on Angewandte Chemie-international Edition was chosen by Asia materials as featured highlight. Currently, his research interest includes the exploration of the intelligent nanoparticles whose properties can be responsive to biological signals as well as the manually controlled external stimulus and further seek their biomedical application, especially in drug delivery, such as intracellular drug delivery and treatment for tumor drug resistance.

SELECTED PUBLICATIONS
1 Xiao-Jun Cai, Hai-Qing Dong, Wen-Juan Xia, Hui-Yun Wen, Xue-Quan Li, Jin-Hai Yua, Yong-Yong Li* (Corresponding author) and Dong-Lu Shi, Glutathione-mediated Shedding of PEG Layers Based on Disulfide-Linked Catiomers for DNA Delivery, Journal of Materials Chemistry, 2011, DOI: 10.1039/C1JM11693B(IF:5.099)
2 Xue-Quan Li, Hui-Yun Wen, Hai-Qing Dong, Wei-Ming Xuea, Giovanni M. Paulettic, Xiao-Jun Cai, Wen-Juan Xia, Donglu Shi and Yong-Yong Li* (Corresponding author), Self-assembling Nanomicelles of a Novel Camptothecin Prodrug Engineered with a Redox-responsive Release Mechanism, Chem. Commun., 2011, 47, 8647-8649. (IF:5.787)
3 Tian-Bin Ren, Wen-Juan Xia, Hai-Qing Dong, Yong-Yong Li* (Corresponding author), Sheddable micelles based on disulfide-linked hybrid PEG-polypeptide copolymer for intracellular drug delivery, Polymer, 2011, 52, 3580-3586. (IF:3.828)
4 Yong-Yong Li, Hai-Qing Dong, Yun Liu, Han Cheng, Cao Li, Wang Xiao, Cong Chang, Shou-Hu Hua, Xuan Zeng, Si-Xue Cheng, Xian-Zheng Zhang, Zhuo RX, Supramolecular polymer micelles prepared by steric effect tuned self-assembly: a new strategy for self-assembly, Soft Matter, 2011, 7, 4839-4844 (IF:4.457)
5 Tian-Bin Ren, Yue Feng, Zhong-Hai Zhang, Lan Li, Yong-Yong Li* (Corresponding author), Shell-sheddable micelles based on star-shaped poly(ε-caprolactone)-SS-poly(ethyl glycol) copolymer for intracellular drug release. Soft Matter, 2011, Soft Matter, 2011, 7, 2329-2331. (IF:4.457)
6 Hui-Yun Wen, Hai-Qing Dong, Wen-juan Xie, Yong-Yong Li* (Corresponding author) Kang Wang, Giovanni M. Pauletti and Dong-Lu Shi, Rapidly disassembling nanomicelles with disulfide-linked PEG shells for glutathione-mediated intracellular drug delivery Chem. Commun., 2011, 47, 3550-3552.(IF:5.787)
7 Hai-Qing Dong, Yong-Yong Li* (Corresponding author), Hui-Yun Wen, Meng Xu, Li-Jian Liu, Zhuo-Quan Li, Fang-Fang Guo, Dong-Lu Shi *, Highly Efficient Drug Delivery Nanosystem by L-Phenylalanine Triggering Based on Supramolecular Polymer Micelles. Macromolecular Rapid Communications, 2011, 32, 540-545. (IF:4.365)
8 Kang Wang, Hai-Qing Dong, Hui-Yun Wen, Meng Xu, Cao Li, Yong-Yong Li*, (Corresponding author),Helen N Jones, Dong-Lu Shi, Xian-Zheng Zhang, Novel vesicles self-assembled from amphiphilic star-armed PEG-polypeptide hybrid copolymers for drug delivery. Macromolecular Bioscience, 2010, 11, 65-71. (IF:3.458)
9 Yong-Yong Li, Han Cheng, Jing-Ling Zhu et al. Temperature and pH sensitive multi-colored micellar complexes. Advanced Materials, 2009, 21, 2402-2406. (IF:10.857)
10 Yong-Yong Li, Han Cheng, Zhi-Guo Zhang et al. Cellular internalization and in vivo tracking of thermosensitive luminescent micelles based on luminescent lanthanide chelate. ACS Nano, 2008, 2, 125-133. (IF: 9.855)
11 Hai-Qing Dong,* Yong-Yong Li* (Equal contribution), Shao-Jun Cai et al. A facile one-pot construction of supramolecular polymer micelles from a-cyclodextrin and poly(e-caprolactone). Angewandte Chemie International Edition, 2008, 47, 5573-5576. (IF: 12.730 )

 

The Institute for Advanced Materials and Nano Biomedicine (iNANO),
Tongji University, 67 Chifeng Road, Shanghai, 200092, China
Tel: +86-021-65988029    Email: inano@tongji.edu.cn
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