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Yilong Wang, Ph.D. Chao Lin, Ph.D.
Donglu Shi, Ph.D Peng Zhao, Ph.D. Peng Zhao, Ph.D.
Yilong Wang, Ph.D.
Yongyong Li, Ph.D. Bingbo Zhang, Ph.D. Donglu Shi, Ph.D
Yilong Wang, Ph.D.
 

 

王祎龙

副研究员,博士生导师(生物医学工程专业)
同济大学医学院 生物医学工程与纳米科学研究院
实训楼224室,200092
13816761031(MP)     65983706-805(O)
Email: yilongwang@tongji.edu.cn

 
 

教育背景  
2003.9-2009.3  博士 应用化学专业 上海交通大学 (硕博联读)
2007.9-2008.9  博士联合培养  美国华盛顿大学(国家留学基金委公派研究生项目)
1994.9-1998.7  学士 塑料工程专业 青岛科技大学 

工作经历
2013.12-至今 同济大学 生物医学工程与纳米科学研究院 副研究员,博士生导师(生物医学工程专业)
2009.7-2013.11 同济大学 先进材料与纳米生物医学研究院 讲师
1998.7-2003.8 重庆庆兰实业有限公司 生产技术设备部 工艺主管
研究兴趣
1. 基于肿瘤细胞能量代谢异常行为的新型CTC捕获及一体化检测技术平台研发;
2. 基于癌症患者外周血循环肿瘤细胞捕获的分子分型、药敏、三维器官构建等研究;
3. 磁性免疫层析精确定量POCT技术平台的应用转化;
4. 磁珠-微流控平台的微生物检测系统开发;
5. 蛋白冠修饰纳米颗粒与细胞间的相互作用;

学术兼职
中国化学会会员 《生物医学工程学杂志》青年编委
Nanoscale, Chemical Communications, Langmuir, Nanotheranostics, Journal of Harzard Materials, Journal of Polymer Science,Part A, Chemical Engineering Journal, Materials Research Bulletin, Journal of Applied Polymer Science, Internation journal of Nanomedicine等多家国际学术期刊审稿专家

获奖情况
2013年 第十四届全国生物材料大会优秀口头报告奖
2012年 同济大学青年英才计划
2011年 同济大学纳米院优秀科研奖
2007年 上海研究生学术论坛最佳论文宣讲奖及优秀论文奖

学术会议、学术交流
2018.5  第二届中国微米纳米技术学会产业创新(西安),口头报告
2017.7  再生医药生物材料及生物制造国际会议(南京),口头报告
2016.12  国际纳米生物与医学学术会议(福州),口头报告
2016.11  磁共振技术暨纳米生物医学应用研讨会 (上海),口头报告
2013年  第十四届全国生物材料大会 口头报告
2007.9   今日材料(Materials Today)亚洲学术交流会议,口头报告
2007.8  韩国汉阳大学纳米科技研究院及生物微芯片加工实验室学术访问,口头报告
2007.6  China Nano(中国纳米)国际会议 墙报

主持纵向项目
[1] 国家自然科学基金面上项目“基于人源性组织异种移植瘤(PDTX)模型的新型miRNA纳米载体构建及其治疗效应研究”(31571018);起止时间:2016.01-2019.12;
[2] 上海市科委“科技创新行动计划”生物医药领域科技支撑项目“前列腺癌血清标记物free PSA/total PSA联合检测的磁性免疫层析试剂盒样品的试制”(15441905900);起止时间:2015.07-2019.09; (已结题)
[3] 上海市自然科学基金项目“miRNA-介孔Fe3O4纳米晶簇新型复合系统的构建及其对头颈鳞癌细胞生长抑制效应的研究”(15ZR1443200);起止时间:2015.01-2017.12;(已结题)
[4] 上海市科委引导项目“结核杆菌纳米探针检测新方法研究”(124119a1500);起止时间:2012.10-2015.9;共同主持; (已结题)
[5] 国家自然科学基金青年基金项目“含双功能基团无机/有机非对称纳米磁性复合材料的可控制备”(51003077);起止时间:2011.01-2013.12;(已结题)
[6] 中央高校基本科研项目“石墨烯/磁性复合纳米材料合成及水处理应用研究”;起止时间:2012.1-2013.12;(已结题)
[7] 污染控制与资源化研究国家重点实验开放课题“石墨烯-磁性纳米材料的制备及其对典型重金属的去除研究”(PCRRF11003);起止时间:2011.9-2012.12;(已结题)
[8] 同济大学青年优秀教师项目“非对称形貌及表面功能化的无机/聚合物磁性复合微球的可控制备”(2009KJ074);起止时间:2010.9-2013.12;(已结题)

参与项目

[9] 国家自然科学基金面上项目“基于新型纳米结构的痕量肿瘤细胞检测方法研究”(51173135);起止时间:2012.01-2015.12;骨干;
[10] 上海市科委纳米专项“基于异质纳米结构的痕量肿瘤细胞检测技术研发”(11nm0506100);起止时间:2011.10-2014.9;骨干,已结题;
[11] 国家自然科学基金青年基金项目“纳米材料与共存重金属对浮游微生物的作用与机理”(21007048);起止时间:2011.01-2013.12;骨干,已结题;
[12] 上海市科委纳米专项“食源性致病菌新型快速检测技术研发”;骨干,已结题;
[13] 国家科技部 863项目“纳米技术在海洋病毒快速检测中的应用研究”子课题;已结题;

教学情况

本科生通识课《纳米科学与艺术》,研究生专业选修课《纳米材料与生物医学检测》;

发表论文

  1. Yishu He, Jingwen Qin, Shengming Wu, Haocheng Yang, Huiyun Wen*, Yilong Wang*, Cancer Cell-Nanomaterial Interface: Role of Geometry and Surface Charge of Nanocomposites on the Capture Efficiency and Cell Viability, Biomaterials Science, 2019, DOI: 10.1039/c9bm00037b
  2. Wei Tian, Fan Li, Shengming Wu, Gen Li, Lieying Fan, Xue Qu*, Xinming Jia*, Yilong Wang*, Efficient Capture and T2 Magnetic Resonance Assay of Candida albicans with Inorganic Nanoparticles: Role of Nanoparticle Surface Charge and Fungal Cell Wall, ACS Biomaterials Science & Engineering, 2019, DOI:10.1021/acsbiomaterials.9b00069.
  3. Yilong Wang#; Shuyang Sun#; Zhiyuan Zhang, Donglu Shi, Nanomaterials for Cancer Precision Medicine, Advanced Materials, 2018, 30,(17): 1705660. DOI: 10.1002/adma.201705660 (# Co-first author, review article)
  4. Chang Xu, Qishuai Feng, Haocheng Yang, Guangxue Wang, Liqun Huang, Qianwen Bai,Chuyi Zhang, Yilong Wang*, Yingna Chen, Qian Cheng, Yu Han, Zuoren Yu*, Maciej S. Lesniak, Yu Cheng*, A Light-Triggered Mesenchymal Stem Cell Delivery System for Photoacoustic Imaging and Chemo-Photothermal Therapy of Triple Negative Breast Cancer, Advanced Science, 2018, 5, 1800382.
  5. Jian Zhao#,*, Shengming Wu#, Jingwen Qin, Donglu Shi*, and Yilong Wang*, Electrical-Charge-Mediated Cancer Cell Targeting via Protein Corona-Decorated Superparamagnetic Nanoparticles in a Simulated Physiological Environment, ACS Appl. Mater. Interfaces, 2018, 10, 41986-41998. (# Co-first author)
  6. Xiao Han; Zicheng Deng; Zi Yang; Huanhuan Zhu; Bingdi Chen; Yilong Wang*; Zheng Cui; Rodney C. Ewing; Donglu Shi*, Biomarkerless targeting and photothermal cancer cell killing by surface-electrically-charged superparamagnetic Fe3O4 composite nanoparticles,  Nanoscale,2017, 9, 1457~1465. (Back cover article)
  7. Shuyang Sun#; Yilong Wang#; Rong Zhou; Zicheng Deng; Yong Han; Xiao Han; Wenjie Tao; Zi Yang; Chaoji Shi; Duo Hong; Jiang Li; Donglu Shi*; Zhiyuan Zhang*, Targeting and Regulating of an Oncogene via Nanovector Delivery of MicroRNA using Patient-Derived Xenografts, Theranostics, 2017, 7, 677~693. (# Co-first author, Front cover article)
  8. Huang, Chao ; Sun, Mayu; Yang, Yang ; Wang, Feng ; Ma, Xueqi; Li, Jingquan; Wang, Yilong; Ding, Qiurong; Ying, Hao; Song, Haiyun; et al., Titanium dioxide nanoparticles prime a specific activation state of macrophages, NANOTOXICOLOGY, 2017, 11, 737-750.
  9. Du, Juan; Zhao, Yong; Yang, Zi; Xu, Changhua; Lu, Ying*; Pan, Yingjie; Shi, Donglu; Wang, Yilong*, Influence of controlled surface functionalization of magnetic nanocomposites on the detection performance of immunochromatographic test, Sensors and Actuators B: Chemical, 2016, 237, 817~825.
  10. Han, Xiao; Huang, Shiming; Wang, Yilong*; Shi, Donglu*, Design and development of anisotropic inorganic/polystyrene nanocomposites by surface modification of zinc oxide nanoparticles, Materials Science and Engineering: C, 2016, 64, 87~92.
  11. Bingdi Chen#, Wenjun Le#, Yilong Wang, Zhuoquan Li, Dong Wang, Lei Ren, Ling Lin, Shaobin Cui,Jennifer J. Hu, Yihui Hu, Pengyuan Yang, Rodney C. Ewing, Donglu Shi* ,Zheng Cui*, Targeting Negative Surface Charges of Cancer Cells by Multifunctional Nanoprobes, Theranostics,2016,6(11): 1887-1898. (# Co-first author)
  12. Tian Li, Xiao Han, Yilong Wang*, Feng Wang, Donglu Shi, Preparation of Spherical Caged Superparamagnetic Nanocomposites with Completed Inorganic Shell via a Modified Miniemulsion Technology, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2015,477,84-89.
  13. Hua Yang, Hui Ma, Yilong Wang*, Bingbo Zhang, Lianhua Qin, Zhonghua Liu, Junmei Lu, Xiaochen Huang, Jie Wang, Donglu Shi, Zhongyi Hu*,Detection of Mycobacterium Tuberculosis based on H37Rv binding peptides using surface functionalized magnetic microspheres coupled with quantum dots, International Journal of nanomedicine, e, 2015,10:77-88.
  14. Du Juan; Lu Ying*; Wang Yilong, et al., Properties and Applications of Janus Nanomaterials, Progress in Chemistry, 2014,26 (12):2019-2026.
  15. M.E. Sadat, Ronak Patel, Jason Sookoor, Sergey L. Bud'ko, Rodney C. Ewing, Jiaming Zhang, Hong Xu, YilongWang, Giovanni M. Pauletti, David B. Mast, Donglu Shi, Effect of spatial confinement on magnetic hyperthermia via dipolar interactions in Fe3O4 nanoparticles for biomedical applications, Materials Science and Engineering C,42(2014) 52–63.
  16. Jun Yan, Yingying Liu, Yilong Wang,* Xiaowei Xu, Ying Lu,* Yingjie Pan,Fangfang Guo, Donglu Shi, Effect of Physiochemical Property of Fe3O4 Particle on Magnetic Lateral Flow Immunochromatographic Assay, Sensors & Actuators: B. Chemical, 2014, 197, 129-136.
  17. Feng Wang, Giovanni M. Pauletti, Juntao Wang, Jiaming Zhang, Rodney C. Ewing, Yilong Wang* and Donglu Shi*, Dual Surface-functionalized Janus Nanocomposites of Polystyrene/Fe3O4@SiO2 for Simultaneous Tumor Cell Targeting and Stimulus-induced Drug Release, Advanced Materials, 2013, 25, 3485–3489.
  18. Tian Li,Yilong Wang*,Fangfang Guo,Donglu Shi,Synthesis and Biomedical Applications of Magnetic Nanocomposites with Complex Morphologies, Progress In Chemistry, In press, 2013.
  19. Yulin Tang, Hongguang Guo, Lan Xiao, Naiyun Gao, Shuili Yu, Yilong Wang*, Adsorption behavior and mechanisms of fluoroquinolone antibiotics on the reduced graphene oxide/magnetite composites, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2013, 424, 74– 80.
  20. Yilong Wang, Song Liang, Bingdi Chen, Fangfang Guo, Shuili Yu, Yulin Tang*, Synergistic removal of Pb(II), Cd(II) and humic acid by Fe3O4@mesoporous silica-graphene oxide composites, PLoS One, 2013, 8, e65634:1-8.
  21. Yulin Tang*, Song Liang, Juntao Wang, Shuili Yu, Yilong Wang*, Amino functionalized core-shell magnetic mesoporous composite microspheres for Pb(II) and Cd(II) removal, Journal of Environmental Sciences, 2013, 25, 830-837.
  22. Fangyingkai Wang, Yulin Tang, Bingbo Zhang, Bingdi Chen, Yilong Wang*, Preparation of Novel Magnetic Hollow Mesoporous Silica Microspheres and their Efficient Adsorption, Journal of Colloid & Interface Science 2012, 386, 129-134.
  23. Yulin Tang*, Song Liang, Shuili Yu, Naiyun Gao, Jun Zhang, Haicheng Guo, Yilong Wang*, Enhanced adsorption of humic acid on amine functionalized magnetic mesoporous composite microspheres, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2012, 406, 61- 67.
  24. Yilong Wang*, Fangyingkai Wang, Bingdi Chen, Hong Xu*, Donglu Shi. “Facile one-pot synthesis of yolk–shell superparamagnetic nanocomposites via ternary phase separations” Chemical Communications, 2011, 47, 10350 - 10352.
  25. Yilong Wang*, Hong Xu, Yongsheng Ma, Fangfang Guo, Feng Wang, and Donglu Shi*. “Facile One-Pot Synthesis and Morphological Control of Asymmetric Superparamagnetic Composite Nanoparticles” Langmuir, 2011, 27, pp 7207–7212.
  26. Yilong Wang, Hong Xu, Weili Qiang, Hongchen Gu, and Donglu Shi, “Asymmetric Composite Nanoparticles with Anisotropic Surface Functionalities”,Journal of Nanomaterials, 2009, 620269, 1-5
  27. Yilong Wang, Hong Xu, and Hongchen Gu*, Synthesis of Raspberry-Like SiO2/Polystyrene Nanocomposite Particles via Miniemulsion Polymerization, Journal of Nanoscience and Nanotechnology, 2009, 9, 1571-1576.
  28. Yilong Wang, Pedro H. C. Camargo, Sara E. Skrabalak, Hongchen Gu, and Younan Xia*, “A Facile, Water-Based Synthesis of Highly Branched Nanostructures of Silver”,Langmuir, 2008, 24, 12042-12046.
  29. Weili Qiang#, Yilong Wang#, Ping He, Hong Xu*, Hongchen Gu, and Donglu Shi, “Synthesis of Asymmetric Inorganic/Polymer Nanocomposite Particles via Localized Substrate Surface Modification and Miniemulsion Polymerization”, Langmuir, 2008, 24, 606-608. (co-first author)

 
已授权专利
[1] 一种磁性荧光双功能氧化硅空心微球的制备方法,王祎龙;马方;陈炳地;张兵波;郭方方;时东陆;专利号:ZL 2011 1 0132719.7;
[2] 具有核壳结构及表面各向异性双功能团的磁性二氧化硅微球及其制备方法,王祎龙;张兵波;郭方方;时东陆;专利号:ZL 2011 1 0029024.6;
[3] 一种壳层中包埋磁性纳米颗粒的介孔氧化硅空心微球的制备方法,王祎龙;唐玉霖;王方英凯;专利号:ZL 201110344263.0;
[4] 具有非对称结构及表面各向异性双功能基团的磁性氧化硅聚合物复合微球的制备方法,王祎龙;时东陆;专利号:ZL 201310182495.X;
[5] 一种蛋黄-蛋壳结构的氧化锌三元复合纳米材料及其制备方法,王祎龙,韩筱,时东陆,申请号:201410253569.9,申请日期:2014.6.10,授权公告日:2016.4.20,专利号:ZL 201410253569.9
[6] 一种由两种高分子共修饰的生物相容性磁性微球及其制备方法,王祎龙,李恬,韩筱,时东陆,申请号:201410305539.8,申请日期:2014.7.1,授权公告日:2016.6.15,专利号:ZL 201410305539.8
[7] 一种磁性纳米复合材料的制备方法、由该方法制备的产品及其应用,唐玉霖;王祎龙;于水利; 专利号:ZL 2011 1 0407318.8;
[8] 一种高性能锂离子电池负极材料石墨烯负载纳米氧化亚钴的制备方法,陈炳地;郭方方;王祎龙;张兵波;时东陆;专利号:ZL 2011 1 0443045.2;

申请发明专利

[9] 一种可吸附水中污染物的氧化石墨烯磁性介孔氧化硅复合材料的制备方法,王祎龙;唐玉霖;郭方方;申请号:201310378526.9,申请日期:2013.8.28;
[10] 一种磁/金纳米复合粒子的制备方法, 王祎龙,杨子,申请号:201710180445.6,申请日期:2017.3.24,公开日期:2017.8.11.

研究生培养:

独立指导硕士毕业生3人(其中1人加入强生公司,1人前往美国辛辛那提大学医学院攻读博士学位),联合指导博士毕业生1人(加入GE公司创研部门)和硕士毕业生8人(包括同济大学环境学院、医学院、附属肺科医院,上海海洋大学、青岛科技大学、华东理工大学、西北大学等高校的联合培养研究生);目前指导在读博士研究生1名和硕士研究生2名;

欢迎有细胞生物学、材料学、生物医学工程学专业背景和实验基础的,对纳米生物检测、纳米-生物界面相互作用基础研究以及肿瘤液体活检的纳米-微流控集成平台的研发及转化应用有兴趣的同学报考硕士或者博士研究生!



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