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Title: A Journey toward Better Glucose Monitoring through Nano-Engineering

Reporter: Guigen Zhang, Ph.D., FAIMBE, Professor of Bioengineering, Clemson University, USA

Inviter: Dr. Bingbo Zhang
Date&Time: 16th, Nov. 2015. 10:00 am
Location: 同济大学医学院纳米院219会议室(南校区高等技术学院大楼纳米院219室)
In this talk, I will present a whole-spectrum view of the interdependence between surface modification (both physically and chemically) and key parts of a biosensor including electrode surface area, electrode functionalization, enzyme stability, and mass transport for the development of nanostructure based biosensors. After a brief overview of some basics about biosensors, I will discuss the role of electrode surfaces, nanoscale surface modification via physical and chemical means for surface enhancement and functionalization through case studies of glucose detection. After that, I will go over the insight and lessons we learned in our efforts to further improve this type of glucose sensors through the use of gold nanoparticles for improving the stability of enzymes and for prolonging the sensor’s functionality, and through the implementation of a fluidic platform with microchannel for fluid transport and target detection.
Reportor Introduction:

Guigen Zhang is a tenured full professor (since 2008) in the Department of Bioengineering at Clemson University in South Carolina, USA – the birthplace of the field of Biomaterials. He is the Executive Director of the Institute for Biological Interfaces of Engineering (IBIOE), Director of Call Me Doctor (CMD) Fellowship Program, and Associate Chair of Department of Bioengineering. Prof. Zhang is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE) and the Founding President of the Chinese Association for Biomaterials.

Over the years, he has published extensively in the areas of biomechanics, biomaterials and biosensors and his research has been funded by diverse funding sources ranging from federal agencies such as National Institutes for Health and National Science Foundation, to private foundations like the Gates Foundation, to venture groups and state-level startup funds. His current research interests include Orthopedic Biomechanics and Biomaterials, Testing and Evaluation of Biomaterials, Micro/Nanotechnology Based Biosensor, and Computational Bioengineering. He holds numerous patents and have extensive experiences with business startups. His recent books include “Computational Bioengineering” published by CRC Taylor & Francis group, and “Nanoscale Surface Modification for Enhanced Biosensor” published by Springer.

Being a national and international leading scholar in areas of biomaterials, biosensors and nanotechnology, he has been constantly invited to serve on expert review panels by the U.S. NIH, NSF, CDMPR and DTRA on subjects ranging from nanotechnology, biomaterials and biointerfaces, biotechnology, sensors and biosensors, to nanoscale drug delivery, among others, and Canadian First Research Excellent Fund. Moreover, he is also a frequent invited speaker in the world-wide policy-making and business venture circles. For example, in December 2014 he delivered an invited keynote at the Venture Biomed Conference in Verbier Switzerland and in July 2009 he gave an invited lead presentation at the OECD Conference on Potential Environmental Benefits of Nanotechnology (OECD: Organization for Economic Co-operation and Development, based in Paris, France).


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People Home Research Facilities Student News Seminar Yao Qin, Ph.D. Bingbo Zhang, Ph.D.